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What is Azilect?

Azilect (rasagiline) is used to treat the symptoms of Parkinson’s disease such as stiffness, shakiness, spasms. difficulty moving and periods of slow movement or stiffness. Azilect may be used by itself or alongside another medication. Rasagiline is an MAO inhibitor and works by increasing the levels of dopamine, norepinephrine, serotonin and other natural substances in the brain.  

Always read the patient information and instructions carefully before using this medication. Follow your doctor’s directions.

• Take this medication with or without food.
• Azilect may be taken by itself or with other medications and your dose will reflect this. Always follow your doctor’s directions.
• Azilect may be used as part of a treatment program which includes a special diet.
• Tell your doctor if your symptoms do not improve. Do not stop taking this medication suddenly as you may have unpleasant side effects.

Make sure to tell your doctor and pharmacist:

• If you have any drug or other allergies.
• Which other prescription and non-prescription medications you currently take.
• Your medical history especially of kidney disease, liver disease, high blood pressure or low blood pressure.
• If you are pregnant, planning pregnancy or breast feeding.

Also be aware that:

• People with Parkinson’s disease may have a high risk of skin cancer. Ask your doctor for symptoms to watch out for.
• You may not be able to eat certain types of cheese while taking Azilect and for two weeks after. Ask your doctor for more information.
• Rasagiline can affect your reactions and thinking. Do not drive, operate machinery or do any other activity requiring alertness until it can be done safely.

Common Azilect side effects may include but are not limited to:

• Dizziness or drowsiness.
• Stomach pain, abdominal pain or nausea.
• Heartburn.
• Joint pain.
• Dry mouth.
• Weight loss.

Contact your doctor if you experience any of the following side effects of Azilect:

• Worsening muscle stiffness, twitching or uncontrollable movements.
• Easy bruising or bleeding.
• Mental or mood changes such as depression, confusion or hallucinations.
• Falling asleep suddenly during usual daily activities. If this happens do not drive or do any other potentially dangerous activities until you have discussed this with your doctor. Drinking alcohol or taking other medications which cause drowsiness can increase the chances of this.
• Fainting or loss of balance.
• Swollen legs or ankles.
• Unusual strong urges such as increased sexual or gambling urges.
• Signs of extremely high blood pressure such as severe headache, vision changes, sudden sensitivity to light, widened pupils, chest pain, neck stiffness, severe nausea, severe vomiting, sweating, clammy skin or a fast, slow, irregular or pounding heartbeat.
• Signs of serotonin syndrome such as fast heartbeat, loss of coordination, severe dizziness, hallucinations, twitching muscles, unexplained fever, severe nausea, severe diarrhea, severe vomiting, restlessness or unusual agitation.
• Signs of an allergic reaction such as hives, difficulty breathing or a swelling of your face, lips or throat.

What should I do if I miss a dose of Azilect?

Skip your missed dose and take the next dose at the regular time. Do not take two doses of this medication.

What is the Azilect generic alternative?

Generic Azilect is known as rasagiline and is available in the same 0.5mg and 1mg strengths.