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What is Provera?

Provera (medroxyprogesterone) is a medication given for women whose bodies do not make enough of the natural hormone progesterone. It can be used to treat abnormal uterus bleeding and to restore normal menstrual periods in women who have stopped having them as well as for other reasons.

Always read the patient information and instructions carefully before using this medication. Follow your doctor’s directions.

• Provera is typically taken for a few days in a row each month. Follow your doctor’s directions for how and when to take medroxyprogesterone.
• You should have regular exams while taking medroxyprogesterone. Self-examine your breasts for lumps on a monthly basis.
• Tell your doctor if your condition does not improve.

Make sure to tell your doctor and pharmacist:

• If you have any drug or other allergies.
• Which other prescription and non-prescription medications you currently take.
• Your medical history especially of liver disease, stroke, blood clots, cancer, abnormal vaginal bleeding, heart disease, congestive heart failure, heart attack, high blood pressure, high cholesterol, triglycerides, severe pelvic pain, low levels of calcium in your blood, epilepsy, asthma, migraines, thyroid disorder, kidney disease, diabetes or lupus.
• If you have had a recent miscarriage or abortion.
• If you are breast feeding.
• If you smoke or are overweight.

Also be aware that:

• Provera may cause unusual medical test results. Tell all of your treating doctors that you take medroxyprogesterone.
• Provera should not be used during pregnancy as it may cause birth defects.

Common Provera side effects may include but are not limited to:

• Nausea.
• Bloating, weight gain or weight loss.
• Breast tenderness.
• Headaches or dizziness.
• Changes in vaginal discharge.
• Drowsiness.
• Mood swings.

Contact your doctor if you experience any of the following side effects of medroxyprogesterone:

• Unusual vaginal bleeding such as breakthrough bleeding or spotting.
• Mood or mental changes such as memory loss or depression.
• Burning, painful or frequent urination.
• Signs of a problem caused by blood clots such as weakness on one side of the body, slurred speech, chest pain, jaw pain, pain in your left arm, vision changes including blurred or double vision, bulging eyes, sudden severe headaches, confusion, severe dizziness, fainting, cough up blood, trouble breathing, calf pain or swelling which is warm to the touch or a pain, swelling, weakness or redness in your arms or legs.
• Unusual tiredness.
• Breast lumps.
• Swelling of your hands or feet.
• Dark patches on your skin and face, or yellowing eyes or skin.
• Signs of an allergic reaction such as hives, difficulty breathing or a swelling of your face, lips or throat.

What should I do if I miss a dose of Provera?

If you miss a dose of this medication, take it as soon as you remember. If it is almost time for your next dose, then skip your missed dose.

What is the generic alternative to Provera?

Generic Provera is known as medroxyprogesterone and is available in the same 2.5mg, 5mg and 10mg strengths.